Mechanisms of recovery from neutropenia induced by hemodialysis.
نویسندگان
چکیده
منابع مشابه
Differentially regulated cell surface expression of leukocyte adhesion receptors on neutrophils.
To elucidate the molecular mechanisms accounting for hemodialysis-induced neutropenia, the regulation of plasma membrane expression of leukocyte adhesion glycoproteins was investigated by both flow cytometry and immunoprecipitation techniques. The members of the LFA family of integrins, Mac-1/Mo1 (CD11/CD18) and gp150/95 (CD11c/CD18), involved in adhesion of myeloid cells to endothelia and othe...
متن کاملHemodialysis coil-induced transient neutropenia and overshoot neutrophilia in normal man.
Profound transient neutropenia, followed by an overshoot of the neutrophil (N) count to an average of 2.5 ± 1.0 (mean ± 1 SD) times higher than average control N count, has been induced in seven normal subjects by reinfusion of heparinized blood that had been stagnated in a hemodialysis coil for 15 mm. This was similar to the neutropenia-neutrophilia cycle occurring shortly after the initiation...
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The ulcerogenic effect of corticosteroids has always been subject of controversial discussion. In this study, which is a part of another extensive study (the role of neutrophil in induction of gastric mucosal injury by different agents), the effect of prednisolone, as a widely used corticosteroid, on the rat gastric mucosa, was investigated. Prednisolone (1 mg/kg) induced acute mucosal injury (...
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Objective: Chemotherapy-induced neutropenia is one of the main side effects of acute lymphoblastic leukemia (ALL) treatment. In this trial, we evaluated the efficacy of chamomile in management of neutropenia. Materials and Methods: This randomized triple-blind placebo-controlled clinical trial was carried out in 2-18-year-old children with ALL. Particip...
متن کاملEffect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery
INTRODUCTION Neutrophil recovery has been implicated in deterioration of oxygenation and exacerbation of preexisting acute lung injury (ALI). The aim of this study was to investigate whether imatinib or nilotinib was effective on lipopolysaccharide (LPS)-induced ALI during neutropenia recovery in mice. METHODS Mice were rendered neutropenic with cyclophosphamide prior to the intratracheal ins...
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ورودعنوان ژورنال:
- Blood
دوره 38 5 شماره
صفحات -
تاریخ انتشار 1971